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  • HMG-CoA Reductase Inhibitors - StatPearls - NCBI Bookshelf
    HMG-CoA reductase inhibitors (statins) are lipid-lowering medications used in the primary and secondary prevention of coronary heart disease This activity reviews the indications, contraindications, and mechanism of action of statins for the management of coronary heart disease and familial dyslipidemias
  • List of Statins + Uses, Types Side Effects - Drugs. com
    Statins (also called HMG-CoA reductase inhibitors) block an enzyme called HMG-CoA reductase (3-hydroxy-3-methylglutaryl coenzyme A reductase) that is involved in the synthesis of mevalonate, a naturally occurring substance that is used by the body to make sterols, including cholesterol
  • How Do HMG-CoA Reductase Inhibitors Work? - RxList
    β-Hydroxy β-methylglutaryl-CoA (HMG-CoA) reductase inhibitors, more popularly known as statins, work by reducing the cholesterol levels in the body HMG-CoA inhibitors interfere with the ability of the body to build cholesterol from dietary fat
  • HMG-CoA Reductase Inhibitors - PubMed
    HMG-CoA reductase inhibitors (statins) are lipid-lowering medications used in the primary and secondary prevention of coronary heart disease This activity reviews the indications, contraindications, and mechanism of action of statins for the management of coronary heart disease and familial dyslipi …
  • The Increasingly Complex Mechanism of HMG-CoA Reductase
    HMGR is the target of statins that are prescribed to improve the quality of life of millions of people worldwide and, more recently, has been identified as a target for the development of antimicrobial agents
  • HMG-CoA reductase inhibitors
    Clinical trials with a new class of cholesterol-lowering drugs, the HMG-CoA reductase inhibitors, have consistently demonstrated a dose-de-pendent reduction in total and low-density lipoprotein cholesterol levels of up to 30% and 40%, respectively
  • Therapeutic Class Overview HMG CoA Reductase Inhibitors
    There are several classes of medications used to alter lipids including the hydroxymethylglutaryl coenzyme A (HMG CoA) reductase inhibitors (statins), fibric acid derivatives, bile acid sequestrants and nicotinic acid (niacin)
  • What are HMG-CoA Reductase Inhibitors? - BOC Sciences
    HMG-CoA reductase inhibitors can competitively inhibit the production of mevalonate from HMG-CoA, reduce cholesterol production and body content, thereby significantly reducing the incidence of fatal and non-fatal cardiovascular disease events


















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