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  • Cardio protective drugs: Beta-blockers
    Contraindications and side effects The most frequent side effects of beta-blockers include: hypotension, bradycardia, bronchospasm, cold extremities, fatigue, headache, sleep disturbances and increased insulin resistance [1] High-degree AV block is an absolute contraindication (if no pacemaker) [1]
  • NCLEX Cardiovascular Pharmacology Flashcards | Quizlet
    Calcium channel blockers are contraindicated in systolic heart failure because they have a negative inotropic effect Reducing the force of cardiac contractions would be detrimental to systolic hear failure because it would further reduce already limited heart output
  • Beta-blockade in CHF: from contraindication to indication
    When beta-blockers were first introduced, they were initially tested in chronic heart failure (CHF) at full doses and without slow upward titration In this context, they rapidly became contraindicated in CHF because of their negative inotropic properties
  • CCS Guidelines ENGLISH_HF Update 2019 AF and HF_FINAL EN - Heart Failure
    We recommend β-blockers for rate control particularly in those with HFrEF (Strong Recommendation; Moderate-Quality Evidence) We recommend rate-limiting CCBs be considered for rate control in HFpEF (Weak Recommendation; Low-Quality Evidence)
  • Why Are Beta-Blockers Contraindicated in Heart Failure?
    Beta-blockers were initially contraindicated for heart failure due to concerns about their effects on heart rate and contractility However, subsequent research demonstrated that when used correctly, they can significantly improve clinical outcomes for patients with heart failure
  • Beta-blocker contraindications: Are there patients or . . . - Springer
    In this manuscript, we discuss the potential contraindications to β-blockers in heart failure and compare the true risks against the significant benefits
  • Potentially harmful drugs to avoid in heart failure
    risk with dihydropyridines, but use with caution7 Non-dihydropyridine calcium channel blockers are contraindicated in systolic heart failure7, but may be useful in heart failure with preserved ejection fraction
  • Beta-blockers in the treatment of cardiovascular disease
    Second- or third-degree heart block, suspected sick sinus syndrome or acute decompensated heart failure are absolute contraindications for the initiation of beta-blockers These agents should be used cautiously or avoided in patients with systolic BP below 90mmHg or heart rate below 50 beats per minute


















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