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  • Homepage | KCENTRA® (Prothrombin Complex Concentrate [Human])
    KCENTRA is the #1 prescribed 4F-PCC for acute major bleeding, with lower all-cause mortality than plasma See full prescribing and safety information, including boxed warning
  • How KCENTRA works | KCENTRA® (Prothrombin Complex Concentrate [Human])
    KCENTRA ®, Prothrombin Complex Concentrate (Human), is a blood coagulation factor replacement product indicated for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA—eg, warfarin) therapy in adult patients with acute major bleeding or the need for urgent surgery or other invasive procedure
  • What is KCENTRA? | KCENTRA® (Prothrombin Complex Concentrate [Human])
    What is KCENTRA? Urgent warfarin reversal with fast and sustained action vs plasma* The only 4-Factor Prothrombin Complex Concentrate (4F-PCC) indicated for the urgent reversal of acquired coagulation factor deficiency induced by vitamin K antagonist (VKA, eg, warfarin) therapy in adult patients with: Need for urgent surgery invasive procedure or Acute major bleeding
  • KCENTRA Support│ FAQs
    KCENTRA is a purified, heat-treated, nanofiltered, lyophilized, non-activated 4-factor prothrombin complex concentrate (4F-PCC) made from pooled human plasma 14,15 KCENTRA contains all 4 vitamin K–dependent coagulation factors (II, VII, IX and X), and the antithrombotic Proteins C and S
  • Dosage Calculator | KCENTRA® (Prothrombin Complex Concentrate [Human])
    The KCENTRA dosing calculator recommends the dose for your patient based on body weight and pretreatment INR See full prescribing and safety information, including boxed warning
  • Choose KCENTRA Clinician Videos
    Choose KCENTRA–proven in clinical trials, validated in the real world, including the selection of clinician videos to educate oneself
  • TE Events Mortality - Kcentra
    KCENTRA has validated in the largest real-world study on 4F-PCC thromboembolic events and all-cause mortality See full prescribing and safety information, including boxed warning
  • Reimbursement and coding support - Kcentra
    Download the KCENTRA Reimbursement Quick Reference Card Keep key information at hand about payment and coding information in the inpatient and outpatient hospital settings
  • Efficacy | KCENTRA® (Prothrombin Complex Concentrate [Human])
    Head-to-head efficacy data between KCENTRA and plasma Endpoints include effective hemostasis and early INR reduction See full prescribing and safety, information including boxed warning
  • Contact Us | Kcentra® (Prothrombin complex concentrate [human])
    Contact us If you have a question about a medical condition, consult with a healthcare professional or, in the case of an emergency, call 911 immediately You can contact us by phone, fax, or email





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