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anaphylaxis    
n. 过敏性反应

过敏性反应

anaphylaxis
n 1: hypersensitivity reaction to the ingestion or injection of
a substance (a protein or drug) resulting from prior
contact with a substance

anaphylaxis \an`a*phy*lax"is\ n.
([a^]n`[.a]*f[imac]*l[a^]k"s[i^]s or
[a^]n`[.a]*f[i^]*l[a^]k"s[i^]s)
1. [Gr. 'ana` back, way from fy`laxis security,
protection.]

1. (Med.) Hypersensitivity (to a foreign antigen) resulting
from prior contact with the same or a related substance.
[WordNet 1.5 AS]

2. (Med.) An immediate but transient systemic reaction to an
antigenic substance to which a person has become
hypersensitized; it is characterized by the contraction of
smooth muscle and capillary dilation. --[Stedman]
[PJC AS]

Note: The cascade of events is triggered by binding of the
foreign antigen to immunoglobulin E and release of
mediators such as histamine, bradykinin, serotonin, and
slow-reacting substance from mast cells. It involves
more than one organ system. The most commonly involved
organs are skin, cardiovascular, respiratory and
gastrointestinal systems. Anaphylaxis is manifested by
a range of signs and symptoms including pruritus,
urticaria, itching, dyspnea, abdominal pain and
cardiovascular collapse (shock). A severe form of the
reaction is called {anaphylactic shock}. --[Stedman]
[PJC AS]

3. (Med) Anaphylactic shock.
[AS]


anaphylactic shock \anaphylactic shock\ n.
([a^]n`[.a]*f[imac]*l[a^]k"t[i^]k sh[o^]k`) (Med.)
Shock resulting from anaphylaxis[2]. It is a severe form of
physiological shock, often having a fatal outcome, and is
caused by an extreme immunological reaction to antigens. It
is characterized by smooth muscle contraction and capillary
dilation throughout the body, initiated by antibodies of the
IgE class. It is usually seen when an antigen to which a
person has become hypersensitized is injected intravenously
or subcutaneously. It is also called {generalyzed
anaphylaxis} or {systemic anaphylaxis}, and sometimes
{anaphylaxis}. --[Stedman]
[PJC AS]


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  • Managing Allergic Reactions and Anaphylaxis in the Emergency Department
    Anaphylaxis and anaphylactic shock are the most severe, life-threatening forms of allergic reaction, with fast onset and decompensation, requiring urgent airway monitoring and support
  • Treating Severe Allergy And Acute Anaphylaxis . . . - EB Medicine
    Abstract Allergic reactions and anaphylaxis are potentially life-threatening processes that present with a variety of clinical symptoms Emergency clinicians must be able to recognize these presentations and make prompt clinical decisions regarding management of a patient’s airway, treatment options, and disposition of a patient who improves after initial presentation Furthermore, emergency
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    This issue reviews the criteria for diagnosing a pediatric patient with anaphylaxis and offers evidence-based recommendations for first- and second-line treatment, including the use of epinephrine, antihistamines, and corticosteroids Biphasic reactions and fatal anaphylaxis are also discussed
  • Management of Allergic Reactions and Anaphylaxis in the Emergency . . .
    Upon completion of this article, you should be able to: (1) list the most common triggers of allergic reactions and anaphylaxis and describe the pathophysiology; (2) identify and differentiate allergic reactions and anaphylaxis; and (3) manage allergic reactions of all severities and provide safe disposition for patients
  • Anaphylaxis in Pediatric Patients: Early Recognition and Treatment Are . . .
    This issue reviews the criteria for diagnosing a pediatric patient with anaphylaxis and offers evidence-based recommendations for first- and second-line treatment, including the use of epinephrine, antihistamines, and corticosteroids Biphasic reactions and fatal anaphylaxis are also discussed
  • The Pediatric Urgent Care Playbook: Anaphylaxis | CME Test
    To take The Pediatric Urgent Care Playbook: Anaphylaxis CME test, please choose one of the options below: Login Already Purchased?
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    Anaphylaxis and anaphylactic shock are the most severe, life-threatening forms of allergic reaction, with fast onset and decompensation, requiring urgent airway monitoring and support
  • P E D I AT R I C EmERgEnCy mEDICInE
    Anaphylaxis is a diagnosis that all pediatricians and emergency medicine clinicians must be comfortable treating Common teaching is that patients should immediately be treated with epi-nephrine, H1 and H2 receptor blocking antihistamines, and cortico-steroids This treatment regimen is so ingrained that few question the evidence behind these treatments
  • Corticoid Steroid Types, Uses, and Side Effects - EB Medicine
    Although corticosteroids have been used for over half a century, their use for management of many pediatric conditions is controversial This issue reviews the evidence-based role of corticosteroid use for management of acute asthma exacerbations, croup, acute pharyngitis, anaphylaxis, acute spinal injury, and bacterial meningits
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    The diagnosis and management of anaphylaxis Joint Task Force on Practice Parameters, American Academy of Allergy, Asthma, and Immunology, American College of Allergy, Asthma and Immunology, and the Joint Council of Allergy, Asthma and Immunology





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