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  • Sickle Cell Disease - What Is Sickle Cell Disease? | NHLBI, NIH
    Sickle cell disease — also called sickle cell anemia — is a group of inherited disorders that affect hemoglobin , the major protein that carries oxygen in red blood cells Normally, red blood cells are disc-shaped and flexible so they can move easily through the blood vessels
  • Sickle Cell Disease - Sickle Cell Trait | NHLBI, NIH
    People with sickle cell trait carry only one copy of the sickle hemoglobin gene and rarely have any symptoms of sickle cell disease However, in rare instances, some people who have sickle cell trait can experience medical complications
  • Sickle Cell Disease - Symptoms | NHLBI, NIH
    Symptoms of sickle cell disease vary from person to person and can change over time How the disease affects your body affects the type of symptoms you have People who inherit only one copy of the sickle cell gene have sickle cell trait They usually don't have symptoms of sickle cell disease
  • Sickle Cell Disease - Causes and Risk Factors | NHLBI, NIH
    Sickle cell disease is sometimes called sickle cell anemia People have sickle cell trait if they inherit a copy of the sickle cell gene from one parent and a copy of the gene for normal hemoglobin, called hemoglobin A, from the other
  • What is Sickle Cell Trait? Fact Sheet - NHLBI, NIH
    Sickle cell trait occurs when a person has one copy of the sickle cell gene passed down from one parent, and a normal hemoglobin gene from the other parent This fact sheet describes what sickle cell trait is, who is affected, how to know if you have it, and how to live well with sickle cell trait
  • Sickle Cell Disease Research - NHLBI, NIH
    The National Institutes of Health (NIH) has supported research on sickle cell disease — also called sickle cell anemia — since before the NHLBI’s founding in 1948 With each passing decade, the NHLBI has kept a focus on advancing the understanding of sickle cell disease and improving clinical care for people who have it The Institute leads and supports research and programs on sickle
  • Sickle Cell Disease - Diagnosis | NHLBI, NIH
    Testing people with symptoms or newborns for blood and genetic abnormalities can find the presence of sickle cell disease Test results help determine the risk of passing on the disease to future offspring if sickle cell trait is present
  • How Sickle Cell Disease May Affect Your Health - NHLBI, NIH
    Sickle cell disease can cause pain, infections, and joint problems throughout the body It can also lead to severe anemia and complications in specific body parts
  • Enfermedad de Células Falciformes (Sickle cell disease)
    (Sickle cell disease (SCD) is the most common inherited blood disorder in the United States In this fact sheet, learn about the causes, signs and symptoms, diagnosis, and treatment of SCD )
  • Sickle Cell Disease - Treatment | NHLBI, NIH
    Treatment options for sickle cell disease include medicines that lessen symptoms, blood transfusions, blood and bone marrow transplants, and gene therapy treatments Bone marrow transplants and gene therapies are potential cures for some people





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